Performance and working principle of super high resolution microscope
After long-term development of microscope technology, coupled with the successive major scientific research progress in the physics field in recent years, finally, in 2008, a new achievement in the history of microscope development - super high resolution fluorescence microscope was developed by scientists. It is predicted that it will become a good helper for biologists.
The super-resolution optical microscope adopts a new generation of ultra-high-resolution technology, that is, solid-state hemispherical super lens imaging technology, which breaks through the optical diffraction resolution limit of traditional optical microscopes and enables the lateral resolution of the microscope to reach 50nm. With this imaging technology, users can obtain ultra-high resolution color images and retain all the advantages of optical microscopy - fast, simple, non-destructive, full, true color.
Adding a solid hemispherical super lens device to the 100X water immersion objective lens can increase the horizontal resolution from 200nm to 50nm, which is equivalent to the actual effect of the 400X objective lens.
It adopts structured illumination micro-imaging technology with a resolution up to 100nm. It not only has 3D-SIM and 2D-SIM imaging modes, but also provides ultra-fast wide-field imaging and TIRF imaging, which significantly improves the temporal and spatial resolution of imaging. , making super-resolution imaging of living cells a reality. The teachers and students of our school can use this instrument to better understand the life process and the mechanism of disease occurrence, and observe the positioning and distribution of fine structures such as organelles and functional proteins, so as to improve the research level of related disciplines in our school.
