Advantages of Laser Confocal Microscopy in Biological Research
Compared with traditional optical microscopes, laser confocal microscopy features higher resolution, simultaneous observation of multiple fluorescence signals, and the capability to form clear three‑dimensional images. When observing biological specimens, laser confocal microscopy offers the following superiorities:
Continuous scanning of living tissues, cells or cell sections enables acquisition of high‑precision three‑dimensional images of the cytoskeleton, chromosomes, organelles and cell membrane systems.
It provides images with higher contrast and resolution than conventional fluorescence microscopes, while delivering high sensitivity and excellent
protection for specimens.
Acquisition of multidimensional images. It supports 7‑dimensional imaging (XYZaλIt), including XYT, XZT and XT scanning, time‑series scanning, rotational scanning, regional scanning and spectral scanning, along with convenient image processing functions.
Intracellular ion fluorescence labeling. Single or multiple labeling methods can be used to detect and dynamically monitor intracellular pH values as well as concentration ratios and changes of ions such as sodium, calcium and magnesium.
Fluorescence labeling observation. It allows visualization of fluorescent‑probe labeled living biological substances in cells or tissue sections, including membrane markers, chemical substances, biochemical reactions, receptors and ligands, nucleic acids, and more. Multiple substances on the same specimen can be labeled and observed simultaneously.
Cell detection is non‑invasive, safe, reliable and highly repeatable. All data and images can be exported instantly or stored long‑term.
